Centronuclear myopathy (CNM)
- CNM causes muscle weakness from a deficiency in muscle fibres. Signs included reduced muscle tone, muscle weakness, abnormal posture, stiffness, hopping when walking, exercise intolerance, and collapsing when exposed to cold.
- In Labrador Retrievers, signs of weakness are present by 5 months old. Worldwide, 10-16% of labradors are estimated to be carriers or affected.
- Affected Breeds: Australian Cobberdog, Australian Labradoodle, Labrador Retriever, Great Dane
Inherited myopathy of Great Danes (IMGD)
- IMGD is a muscle disorder that occurs in Great Danes. It’s a progressive disease that gets worse over time. Signs typically begin showing from 6 months of age, and many are put to sleep by a year old due to quality-of-life concerns. Affected dogs will have difficulty exercising, tremors brought on by exercise, weakness, muscle wastage, abnormal posture or gait.
- Affected Breeds: Great Dane
